Association of Reperfusion After Thrombolysis With Clinical Outcome Across the 4.5-to 9-Hours and Wake-Up Stroke Time Window A Meta-Analysis of the EXTEND and EPITHET Randomized Clinical Trials

- Campbell, Bruce C. V., Ma, Henry, Desmond, Patricia M., Wijeratne, Tissa, Curtze, Sami, Barber, P. Alan, De Silva, Deidre A., Thijs, Vincent, Levi, Christopher R., Bladin, Christopher F., Sharma, Gagan, Bivard, Andrew, Parsons, Mark W., Donnan, Geoffrey A., Davis, Stephen M., Churilov, Leonid, Yassi, Nawaf, Kleinig, Timothy J., Hsu, Chung Y., Dewey, Helen M., Butcher, Kenneth S., Yan, Bernard

Extending thrombolysis to 4.5-9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data

- Campbell, Bruce C. V., Ma, Henry, Ringleb, Peter A., Parsons, MW, Churilov, Leonid, Bendszus, Martin, Levi, Christopher R., Hsu, Chung, Kleinig, Timothy J., Fatar, Marc, Leys, Didier, Molina, Carlos, Wijeratne, Tissa, Curtze, Sami, Dewey, Helen M., Barber, P. Alan, Butcher, Kenneth S., De Silva, Deidre A., Bladin, Christopher F., Yassi, Nawaf

Influence of occlusion site and baseline ischemic core on outcome in patients with ischemic stroke

- Tian, Huiqiao, Parsons, Mark W., Levi, Christopher R., Lin, Longting, Aviv, Richard I., Spratt, Neil J., Butcher, Kenneth S., Lou, Min, Kleinig, Timothy J., Bivard, Andrew

Intravenous thrombolysis may not improve clinical outcome of acute ischemic stroke patients without a baseline vessel occlusion

- Tian, Huiqiao, Parsons, Mark W., Zhang, Jingfen, Dong, Qiang, Chen, Chushuang, Bivard, Andrew, Levi, Christopher R., Cheng, Xin, Aviv, Richard I., Spratt, Neil J., Kleinig, Timothy J., O'Brien, Billy, Butcher, Kenneth S., Lin, Longting

Influence of penumbral reperfusion on clinical outcome depends on baseline ischemic core volume

- Chen, Chushuang, Parsons, Mark W., Dong, Qiang, Bivard, Andrew, Clapham, Matthew, Oldmeadow, Christopher, Levi, Christopher R., Lin, Longting, Cheng, Xin, Lou, Min, Kleinig, Timothy J., Butcher, Kenneth S.

Advanced imaging improves prediction of hemorrhage after stroke thrombolysis

- Campbell, Bruce C. V., Christensen, Søren, Mlynash, Michael, Olivot, Jean-Marc, Straka, Matus, Bammer, Roland, Albers, Gregory W., Donnan, Geoffrey A., Davis, Stephen M., Parsons, Mark W., Churilov, Leonid, Desmond, Patricia M., Barber, P. Alan, Butcher, Kenneth S., Levi, Christopher R., De Silva, Deidre A., Lansberg, Maarten G.

Moving beyond a single perfusion threshold to define penumbra: a novel probabilistic mismatch definition

- Nagakane, Yoshinari, Christensen, Soren, Donnan, Geoffrey A., Ogata, Toshiyasu, Churilov, Leonid, Ma, Henry, Parsons, Mark W., Desmond, Patricia M., Levi, Christopher R., Butcher, Kenneth S., Davis, Stephen M.

EPITHET: positive result after reanalysis using baseline diffusion-weighted imaging/perfusion-weighted imaging co-registration

- Nagakane, Yoshinari, Christensen, Soren, Bladin, Christopher F., De Silva, Deidre A., Fink, John, Kimber, Thomas E., Schultz, David W., Muir, Keith W., Tress, Brian M., Desmond, Patricia M., Davis, Stephen M., Donnan, Geoffrey A., Brekenfeld, Caspar, EPITHET Investigators,, Ma, Henry, Churilov, Leonid, Parsons, Mark W., Levi, Christopher R., Butcher, Kenneth S., Peeters, Andre, Barber, Alan

Fluid-attenuated inversion recovery hyperintensity in acute ischemic stroke may not predict hemorrhagic transformation

- Campbell, Bruce C. V., Costello, Craig, Lansberg, Maarten G., Mlynash, Michael, Olivot, Jean-Marc, Straka, Matus, Bammer, Roland, Albers, Gregory W., Donnan, Geoffrey A., Davis, Stephen M., Christensen, Soren, Ebinger, Martin, Parsons, Mark W., Desmond, Patricia M., Barber, P. Alan, Butcher, Kenneth S., Levi, Christopher R., De Silva, Deidre A.

Pathophysiological determinants of worse stroke outcome in atrial fibrillation

- Tu, Hans T. H., Campbell, Bruce C. V., Bladin, Christopher F., Donnan, Geoffrey A., Davis, Stephen M., Christensen, Soren, Collins, Marnie, De Silva, Deidre A., Butcher, Kenneth S., Parsons, Mark W., Desmond, Patricia M., Barber, P. Alan, Levi, Christopher R.

Regional very low cerebral blood volume predicts hemorrhagic transformation better than diffusion-weighted imaging volume and thresholded apparent diffusion coefficient in acute ischemic stroke

- Campbell, Bruce C. V., Christensen, Søren, Donnan, Geoffrey A., Davis, Stephen M., Butcher, Kenneth S., Gordon, Ian, Parsons, Mark W., Desmond, Patricia M., Barber, P. Alan, Levi, Christopher R., Bladin, Christopher F., De Silva, Deidre A.

The benefits of intravenous thrombolysis relate to the site of baseline arterial occlusion in the echoplanar imaging thrombolytic evaluation trial (EPITHET)

- De Silva, Deidre A., Brekenfeld, Caspar, Davis, Stephen M., Ebinger, Martin, Christensen, Søren, Barber, P. Alan, Butcher, Kenneth S., Levi, Christopher R., Parsons, Mark W., Bladin, Christopher F., Donnan, Geoffrey A.

Visual assessment of perfusion-diffusion mismatch is inadequate to select patients for thrombolysis

- Campbell, Bruce C. V., Christensen, Søren, Davis, Stephen M., Foster, Sarah J., Desmond, Patricia M., Parsons, Mark W., Butcher, Kenneth S., Barber, P. Alan, Levi, Christopher R., Bladin, Christopher F., Donnan, Geoffrey A.

Expediting MRI-based proof-of-concept stroke trials using an earlier imaging end point

- Ebinger, Martin, Christensen, Soren, De Silva, Deidre A., Parsons, Mark W., Levi, Christopher R., Butcher, Kenneth S., Bladin, Christopher F., Barber, Alan, Donnan, Geoffrey A., Davis, Stephen M.

Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial

- Davis, Stephen M., Donnan, Geoffrey A., Parsons, Mark W., Levi, Christopher, Butcher, Kenneth S., Peeters, Andre, Barber, P. Alan, Bladin, Christopher, De Silva, Deidre A., Byrnes, Graham

EPITHET: where next? Authors' reply

- Davis, Stephen M., Donnan, Geoffrey A., Parsons, Mark W., Levi, Christopher, Butcher, Kenneth S., Barber, P. Alan, Bladin, Christopher, De Silva, Deidre A., Peeters, Andre